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IONIS PTP1BRx

PTP-1B Inhibitor

IONIS PTP1BRx is an antisense inhibitor specifically targeting protein tyrosine phosphatase 1B (PTP-1B). This compound exhibits notable antidiabetic activity, making it valuable for research into insulin resistance and the mechanisms underlying type 2 diabetes mellitus, particularly in the context of obesity. Its selective inhibition of PTP-1B allows for a deeper understanding of metabolic dysregulation and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1403406-29-0
Applications	PTP-1B Inhibitor
Synonyms	ISIS 404173

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.