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iP300w

p300 Ligand

iP300w is a selective inhibitor of the histone acetyltransferase p300 (KAT3B), known for its role in chromatin remodeling and transcriptional regulation. This compound demonstrates significant biological activity by disrupting p300-mediated acetylation processes, making it a valuable tool in studying epigenetic modifications. Additionally, iP300w can be utilized in the synthesis of PROTAC BT-O2C, facilitating research in targeted protein degradation applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3055107-60-0
Applications	p300 Ligand
Formula	C₂₈H₂₄F₅N₅O₅
Molecular Weight	605.51
SMILES	O=C(O)CN1N=CC(C2=CC3=C([C@](C(N4CC(N(CC5=CC=C(F)C=C5)[C@@H](C)C(F)(F)F)=O)=O)(C[C@H]3F)NC4=O)C=C2)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.