IRAK inhibitor 6 (IRAK-IN-6)

Name: IRAK inhibitor 6 (IRAK-IN-6)
Brand: Adooq Bioscience
SKU: A11460
Rating: 5 (288 reviews)

Catalog No.: A11460

IRAK inhibitor

IRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines.

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IRAK inhibitor 6 (IRAK-IN-6) 1042672-97-8 IRAK inhibitor

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Grouped product items
Size	Price	Stock
1mg	$40.00	In stock
5mg	$115.00	In stock
10mg	$175.00	In stock
25mg	$305.00	In stock
50mg	$450.00	In stock
100mg	$610.00	In stock
*10mM 1mL in DMSO**	$130.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	IRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines.

Product Information

Catalog Num	A11460
Formula	C20H20N4O3S
Molecular Weight	396.46
CAS Number	1042672-97-8
SMILES	O=C(C1=CSC(C2=CC=CN=C2)=N1)NC3=CC=C(N4CCOCC4)C=C3OC
Synonyms	IRAK-IN-6, IRAK IN 6, IRAKIN6, IRAK inhibitor 6
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	6 mg/mL (15.13 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.23 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

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