Fig. 1 · Structure

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ISIS 14803

HCV inhibitors

ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that specifically targets hepatitis C virus (HCV) RNA by binding to the translation initiation region of the internal ribosome entry site (IRES). This binding effectively inhibits HCV protein expression in cell culture, making ISIS 14803 a valuable tool for research into antiviral strategies and the molecular mechanisms of HCV replication. Its precision in targeting HCV RNA positions it as a significant reagent for studying HCV biology and developing therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 223603-41-6
Applications HCV inhibitors

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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