ISO-92 is a selective inhibitor of migration inhibitory factor (MIF) with an IC50 of 550 nM. This compound effectively reduces inflammatory activity and demonstrates a dose-dependent inhibition of hypoxia-induced proliferation in the CCL-210 cell line. In mouse models of hypoxia, ISO-92 significantly decreases the thickness of the pulmonary vascular wall. Its unique mechanism makes ISO-92 a valuable tool for investigating inflammatory and neurological disorders.
ISO-92 is a selective inhibitor of migration inhibitory factor (MIF) with an IC50 of 550 nM. This compound effectively reduces inflammatory activity and demonstrates a dose-dependent inhibition of hypoxia-induced proliferation in the CCL-210 cell line. In mouse models of hypoxia, ISO-92 significantly decreases the thickness of the pulmonary vascular wall. Its unique mechanism makes ISO-92 a valuable tool for investigating inflammatory and neurological disorders.
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