MKA031 is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF) with an IC50 value of 1.7 μM. This compound disrupts the interaction between MIF and AIF, impedes MIF nuclear translocation, and interferes with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced cell death. MKA031 is particularly useful for research applications focused on chronic hepatitis C virus infection and related cellular pathways.
MKA031 is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF) with an IC50 value of 1.7 μM. This compound disrupts the interaction between MIF and AIF, impedes MIF nuclear translocation, and interferes with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced cell death. MKA031 is particularly useful for research applications focused on chronic hepatitis C virus infection and related cellular pathways.
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