Fig. 1 · Structure

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Isoandrographolide

NLRP3 Inhibitor

Isoandrographolide is a selective inhibitor of the NLRP3 inflammasome, known for its potential to modulate inflammatory responses. This compound exhibits significant hepatoprotective effects and promotes cell differentiation. Research applications include studying the role of NLRP3 in inflammatory diseases and exploring therapeutic strategies for conditions such as silicosis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 4176-96-9
Applications NLRP3 Inhibitor
Formula C20H30O5
Molecular Weight 350.45
SMILES
C[C@]12[C@@]3([H])[C@](OC(C4=CCOC4=O)C3)(CC[C@]1([H])[C@@](C)([C@@H](CC2)O)CO)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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