Fig. 1 · Structure
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Isoapoptolidin
Mitochondrial F0F1-ATPase Inhibitor
Isoapoptolidin is an inhibitor of the mitochondrial F0F1-ATPase, exhibiting a Ki greater than 100 μM and selective action towards mitochondrial complex V. This compound is valuable for investigating mitochondrial energy metabolism-related disorders, including cancer and neurodegenerative diseases. Its inhibitory properties facilitate studies on the role of ATP synthase in cellular energy regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 476647-30-0 |
| Applications | Mitochondrial F0F1-ATPase Inhibitor |
| Formula | C58H96O21 |
| Molecular Weight | 1129.37 |
| SMILES | C/C1=C\C(C)=C\C(C)=C\[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]2O)/C=C/C(C)=C/CC[C@H](O)[C@@H](OC)C[C@H](O)[C@H]([C@@]3(O)[C@H](C)[C@@H](O)[C@@H](C)[C@](C[C@@H](O[C@H]4C[C@](C)(O)[C@@H](O[C@@H]5O[C@H](C)[C@@H](O)[C@H](OC)C5)[C@H](C)O4)COC)([H])O3)OC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.