ISRIB

Catalog No.: A14302

PERK inhibitor

ISRIB

ISRIB Chemical Structure

CAS NO. 1597403-47-8

ISRIB, the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $200.00

Special Price $160.00

50 mg

Regular Price: $350.00

Special Price $280.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

ISRIB, the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
Targets
PERK
5 nM
In vitro DMSO 4 mg/mL (8.86 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.16 mL 110.78 mL 221.56 mL
0.5 mM 4.43 mL 22.16 mL 44.31 mL
1 mM 2.22 mL 11.08 mL 22.16 mL
5 mM 0.44 mL 2.22 mL 4.43 mL

*The above data is based on the productmolecular weight 451.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14302
Actions Inhibitor
M. Wt 451.34
Formula C22H24Cl2N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1597403-47-8
Synonyms N/A
SMILES C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl

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