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Istaroxime oxalate

Na+/K+ ATPase Inhibitor

Istaroxime oxalate is a Na+/K+ ATPase inhibitor, functioning as an inotropic agent with an IC50 of 0.11 μM. This reagent enhances the force of contraction in guinea pig atria and increases twitch amplitude in isolated guinea pig myocytes, demonstrating significant potential for cardiac function studies. Its ability to exert these effects without inducing lethal arrhythmias makes it valuable for research in cardiovascular physiology and pharmacology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	203737-94-4
Applications	Na+/K+ ATPase Inhibitor
Formula	C₂₃H₃₄N₂O₇
Molecular Weight	450.53
Synonyms	PST2744 oxalate
SMILES	O=C1CC[C@@]2([H])[C@]3([H])CC([C@@]4([H])C/C(CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=N/OCCN)=O.OC(C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.