Istaroxime oxalate is a Na+/K+ ATPase inhibitor, functioning as an inotropic agent with an IC50 of 0.11 μM. This reagent enhances the force of contraction in guinea pig atria and increases twitch amplitude in isolated guinea pig myocytes, demonstrating significant potential for cardiac function studies. Its ability to exert these effects without inducing lethal arrhythmias makes it valuable for research in cardiovascular physiology and pharmacology.
Istaroxime oxalate is a Na+/K+ ATPase inhibitor, functioning as an inotropic agent with an IC50 of 0.11 μM. This reagent enhances the force of contraction in guinea pig atria and increases twitch amplitude in isolated guinea pig myocytes, demonstrating significant potential for cardiac function studies. Its ability to exert these effects without inducing lethal arrhythmias makes it valuable for research in cardiovascular physiology and pharmacology.
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