Fig. 1 · Structure
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Itopride hydrochloride
AChE/D2DR Inhibitor
Itopride hydrochloride is a potent acetylcholinesterase (AChE) inhibitor and dopamine D2 receptor antagonist. By enhancing gastric motility through its antidopaminergic and anti-AChE effects, Itopride hydrochloride serves as an effective gastrointestinal prokinetic agent. This compound is particularly useful for investigating conditions such as gastroesophageal reflux disease (GERD) and related gastrointestinal disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 122892-31-3 |
| Applications | AChE/D2DR Inhibitor |
| Formula | C20H27ClN2O4 |
| Molecular Weight | 394.89 |
| Synonyms | HSR803 |
| SMILES | O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC=C(OC)C(OC)=C2.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.