Itraconazole-d3 is a deuterium-labeled derivative of Itraconazole, a triazole antifungal that targets lanosterol 14α-demethylase, a cytochrome P450 enzyme, with an IC50 of approximately 800 nM. This compound acts as a potent antagonist of the Hedgehog (Hh) signaling pathway, and exhibits notable anticancer and antiangiogenic properties. Additionally, Itraconazole-d3 functions as an oxysterol-binding protein (OSBP) inhibitor, making it a valuable tool for studying fungal infections, cancer biology, and metabolic pathways in research settings.
Itraconazole-d3 is a deuterium-labeled derivative of Itraconazole, a triazole antifungal that targets lanosterol 14α-demethylase, a cytochrome P450 enzyme, with an IC50 of approximately 800 nM. This compound acts as a potent antagonist of the Hedgehog (Hh) signaling pathway, and exhibits notable anticancer and antiangiogenic properties. Additionally, Itraconazole-d3 functions as an oxysterol-binding protein (OSBP) inhibitor, making it a valuable tool for studying fungal infections, cancer biology, and metabolic pathways in research settings.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
