Fig. 1 · Structure
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Itriglumide
CCKBR Antagonist
Itriglumide is a potent and selective antagonist of the cholecystokinin B receptor (CCKBR), exhibiting an IC50 of 2.3 nM. It effectively antagonizes gastrin response in a dose-dependent manner, with an IC50 of 5.9 nM. Itriglumide demonstrates significant antisecretory and antiulcer properties, making it a valuable reagent for research in gastrointestinal pharmacology and related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 201605-51-8 |
| Applications | CCKBR Antagonist |
| Formula | C33H38N2O4 |
| Molecular Weight | 526.67 |
| Synonyms | CR 2945 |
| SMILES | O=C(C1=C(C(C)=CC(C)=C1)NC(C[C@@H](C2=CC=CC3=CC=CC=C23)CC(O)=O)=O)N4CCC5(CCCC5)CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.