Itriglumide is a potent and selective antagonist of the cholecystokinin B receptor (CCKBR), exhibiting an IC50 of 2.3 nM. It effectively antagonizes gastrin response in a dose-dependent manner, with an IC50 of 5.9 nM. Itriglumide demonstrates significant antisecretory and antiulcer properties, making it a valuable reagent for research in gastrointestinal pharmacology and related studies.
Itriglumide is a potent and selective antagonist of the cholecystokinin B receptor (CCKBR), exhibiting an IC50 of 2.3 nM. It effectively antagonizes gastrin response in a dose-dependent manner, with an IC50 of 5.9 nM. Itriglumide demonstrates significant antisecretory and antiulcer properties, making it a valuable reagent for research in gastrointestinal pharmacology and related studies.
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