IU1-47

Catalog No.: A18615

USP14 inhibitor

IU1-47

IU1-47 Chemical Structure

CAS NO. 670270-31-2

IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $160.00

Special Price $128.00

10 mg

Regular Price: $260.00

Special Price $208.00

50 mg

Regular Price: $920.00

Special Price $736.00

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Biological Activity

IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.23 mL 151.13 mL 302.25 mL
0.5 mM 6.05 mL 30.23 mL 60.45 mL
1 mM 3.02 mL 15.11 mL 30.23 mL
5 mM 0.6 mL 3.02 mL 6.05 mL

*The above data is based on the productmolecular weight 330.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18615
Actions Inhibitor
CAS No. 670270-31-2
Formula C19H23ClN2O
M. Wt 330.85
Purity >98%
Synonyms IU1-47; IU1 47; IU147
SMILES CC1=CC(C(CN2CCCCC2)=O)=C(C)N1C3=CC=C(Cl)C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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