Fig. 1 · Structure

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IU2-6

USP14 Inhibitor

IU2-6 is a selective inhibitor of the deubiquitinase USP14. By inhibiting the deubiquitinating activity associated with the proteasome, IU2-6 prevents the rescue of substrates from degradation and enhances overall proteasomal activity. This compound is valuable for research applications focusing on neurodegenerative diseases and related cellular processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1356074-25-3
Applications USP14 Inhibitor
Formula C14H17N3S
Molecular Weight 259.37
SMILES
N=1C=NC(=C2C1SC3=C2CCCC3)N(C)C4CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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