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Biological Activity
IV-23 (Compound 20) is a potent Noxa mediated apoptosis inducer, and it is a promising anticancer agent with potential. IV-23 inhibits cell growths in vitro and in vivo, reduces colony formation, arrests cell cycle at M phase, and induces esophageal squamous cell carcinoma (ESCC).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.49 mL | 127.47 mL | 254.95 mL |
| 0.5 mM | 5.1 mL | 25.49 mL | 50.99 mL |
| 1 mM | 2.55 mL | 12.75 mL | 25.49 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 392.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18979 |
|---|---|
| Actions | Inducer |
| CAS No. | 2326007-49-0 |
| Formula | C18H18BrNO4 |
| M. Wt | 392.24 |
| Purity | >98% |
| Synonyms | IV23, IV 23 |
| SMILES | O=C(N1CCC2=C1C=CC(Br)=C2)C3=CC(OC)=C(OC)C(OC)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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