Ivacaftor hydrate

Catalog No.: A15133

CFTR potentiator

Ivacaftor hydrate

Ivacaftor hydrate Chemical Structure

CAS NO. 1134822-07-3

Ivacaftor hydrate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.

Availability: In stock

Package Price Qty
5 mg
$76.00
10 mg
$130.00
50 mg
$386.00
100 mg
$773.00
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Biological Activity

Ivacaftor hydrate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.36 mL 121.8 mL 243.6 mL
0.5 mM 4.87 mL 24.36 mL 48.72 mL
1 mM 2.44 mL 12.18 mL 24.36 mL
5 mM 0.49 mL 2.44 mL 4.87 mL

*The above data is based on the productmolecular weight 410.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15133
Actions Potentiator
CAS No. 1134822-07-3
Formula C24H30N2O4
M. Wt 410.51
Solubility DMSO
Purity >98%
Synonyms VX-770 hydrate
SMILES CC(C)(C1=C(C=C(C(C(C)(C)C)=C1)O)NC(C2=CNC3=C(C2=O)C=CC=C3)=O)C.O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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