IWP-051

Catalog No.: A60892
Soluble Guanylate Cyclase Agonist
IWP-051 is an agonist for soluble guanylate cyclase, with an EC50 of 290 nM. It effectively stimulates the production of cyclic guanosine monophosphate (cGMP) and shows a synergistic effect with nitric oxide (NO). This compound is suitable for research focusing on cardiovascular function, smooth muscle relaxation, and other cGMP-related signaling pathways. Moreover, IWP-051 demonstrates favorable pharmacokinetic properties in rat models, making it a valuable tool for in vivo studies.
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionIWP-051 is an agonist for soluble guanylate cyclase, with an EC50 of 290 nM. It effectively stimulates the production of cyclic guanosine monophosphate (cGMP) and shows a synergistic effect with nitric oxide (NO). This compound is suitable for research focusing on cardiovascular function, smooth muscle relaxation, and other cGMP-related signaling pathways. Moreover, IWP-051 demonstrates favorable pharmacokinetic properties in rat models, making it a valuable tool for in vivo studies.
Product Information
Catalog NumA60892
FormulaC17H11F2N5O2
Molecular Weight355.30
CAS Number1354041-91-0
SMILESO=C1NC(C2=NN(CC3=CC=CC=C3F)C(C4=NOC=C4)=C2)=NC=C1F
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