Fig. 1 · Structure

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Jasplakinolide probe-1

Drug Derivative

Jasplakinolide probe-1 is a derivative of Jasplakinolide, specifically designed as a probe targeting actin dynamics. This compound exhibits significant anti-proliferative activity by disrupting the balance of actin filament dynamics, which leads to the collapse of cell lamellipodia. Jasplakinolide probe-1 is particularly useful for imaging actin structures within cells when conjugated with a fluorescent dye, facilitating studies in cellular morphology and motility.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1377338-26-5
Applications Drug Derivative
Formula C43H59N5O8
Molecular Weight 773.96
SMILES
O=C(N[C@@H](C1=CC=C(C=C1)O)CC(O[C@H](CC/C=C(C[C@@H](C(N[C@H](C(N2C)=O)CCCCNC(OC(C)(C)C)=O)=O)C)\C)C)=O)[C@H]2CC3=CNC4=CC=CC=C34

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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