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JC-010a

SHP2 Allosteric Inhibitor

JC-010a is a selective allosteric inhibitor of SHP2, a protein tyrosine phosphatase involved in signaling pathways that promote cancer cell proliferation. This compound effectively inhibits the growth of various cancer cell types, making it a valuable tool for studying cancer biology. JC-010a is suitable for research applications aimed at elucidating the role of SHP2 in tumorigenesis and exploring therapeutic strategies against cancers reliant on SHP2 activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2565765-13-9
Applications	SHP2 Allosteric Inhibitor
Formula	C₂₄H₂₁Cl₂N₅S
Molecular Weight	482.43
SMILES	ClC1=CC=CC(C2=NC(N=CC(N3CCC4(CC5=CC=CC=C5[C@H]4N)CC3)=N6)=C6S2)=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.