Fig. 1 · Structure
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JCP-170
ABHD6 inhibitor
JCP-170 is a substituted chloroisocoumarin that functions as an ABHD6 inhibitor. This compound demonstrates potent inhibition of metastatic seeding in the murine cell line 0688M, as well as in human pancreatic ductal adenocarcinoma (PDAC) cell lines. JCP-170 is valuable for research applications focused on cancer metastasis and the role of ABHD6 in tumor progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 120218-98-6 |
| Applications | ABHD6 inhibitor |
| Formula | C24H18ClNO4 |
| Molecular Weight | 419.86 |
| SMILES | O=C(C(C1=CC=CC=C1)C2=CC=CC=C2)NC3=CC=C(C(Cl)=C(OC4=O)OC)C4=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.