Fig. 1 · Structure
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JMV 167
CKK Antagonist
JMV 167 is a potent antagonist of the peripheral cholecystokinin receptor (CKK), exhibiting an IC50 value of 500 nM. This compound is valuable for research applications involving the modulation of digestive processes and appetite regulation. Its role in studying the effects of cholecystokinin signaling makes it an essential tool for investigating therapeutic strategies related to gastrointestinal disorders and metabolic conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 120775-49-7 |
| Applications | CKK Antagonist |
| Formula | C51H68N8O14S |
| Molecular Weight | 1049.20 |
| SMILES | CCCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC(O)=O)C(=O)NCCc1ccccc1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.