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JMV 167

Catalog No.: A59695
CKK Antagonist
JMV 167 is a potent antagonist of the peripheral cholecystokinin receptor (CKK), exhibiting an IC50 value of 500 nM. This compound is valuable for research applications involving the modulation of digestive processes and appetite regulation. Its role in studying the effects of cholecystokinin signaling makes it an essential tool for investigating therapeutic strategies related to gastrointestinal disorders and metabolic conditions.
JMV 167 120775-49-7 CKK Antagonist
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Size Price Stock Qty
25mg
$1,275.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJMV 167 is a potent antagonist of the peripheral cholecystokinin receptor (CKK), exhibiting an IC50 value of 500 nM. This compound is valuable for research applications involving the modulation of digestive processes and appetite regulation. Its role in studying the effects of cholecystokinin signaling makes it an essential tool for investigating therapeutic strategies related to gastrointestinal disorders and metabolic conditions.
Product Information
Catalog NumA59695
FormulaC51H68N8O14S
Molecular Weight1049.20
CAS Number120775-49-7
SequenceBoc-{Tyr(SO3H)}-{Nle}-Gly-Trp-{Nle}-Asp-{2-Phenylethylamine}
Sequence shorteningBoc-{Tyr(SO3H)}-{Nle}-GW-{Nle}-D-{2-Phenylethylamine}
SMILESCCCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC(O)=O)C(=O)NCCc1ccccc1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

GPCR/G Protein > CCK