Fig. 1 · Structure

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JMV 170

CCK-B Agonist

JMV 170 is a selective CCK-B agonist that specifically targets the CCK-B receptor with a binding affinity ten times greater than that for the CCK-A receptor. This compound induces contractile effects in pig smooth muscle cells, exhibiting an EC50 value of 9 pmol/L. JMV 170 is primarily utilized in research applications focusing on gastrointestinal physiology and neurobiology, particularly in studies investigating the roles of cholecystokinin in smooth muscle contractility.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 117829-60-4
Applications CCK-B Agonist
Formula C51H68N8O14S
Molecular Weight 1049.21
SMILES
C([C@@H](C(N[C@H](C(N[C@H](C(NCCC1=CC=CC=C1)=O)CC(O)=O)=O)CCCC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC(OC(C)(C)C)=O)=O)CCCC)=O)=O)C=3C=4C(NC3)=CC=CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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