Fig. 1 · Structure
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JMV 179
CKK Antagonist
JMV 179 is a cholecystokinin receptor (CKK) antagonist with an IC50 of 30 nM. This peptide analog is designed to inhibit CCK receptor activity, making it a valuable tool for studying the physiological and pathophysiological roles of CCK signaling. JMV 179 is utilized in various research applications, particularly in gastrointestinal studies and neuropharmacology, to explore the therapeutic potential of modulating CCK pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 119386-87-7 |
| Applications | CKK Antagonist |
| Formula | C51H67N7O15S |
| Molecular Weight | 1050.18 |
| SMILES | C([C@H](C(N[C@H](C(N[C@H](C(OCCC1=CC=CC=C1)=O)CC(O)=O)=O)CCCC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC(OC(C)(C)C)=O)=O)CCCC)=O)=O)C=3C=4C(NC3)=CC=CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.