Fig. 1 · Structure

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JNJ-17156516

CCK1-receptor Antagonist

JNJ-17156516 is a potent and selective antagonist of the cholecystokinin (CCK)1 receptor. This compound demonstrates significant biological activity in inhibiting CCK-induced signaling, making it valuable for research in gastrointestinal physiology and related disorders. Its oral bioavailability positions it as a useful tool in the exploration of CCK1 receptor functions and therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 649551-06-4
Applications CCK1-receptor Antagonist
Formula C26H22Cl2N2O3
Molecular Weight 481.37
SMILES
O=C([C@@H](CC1=NN(C(C2=CC=C(C(Cl)=C2)Cl)=C1)C3=CC=C(C=C3)OC)C4=CC=CC(C)=C4)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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