JNJ-37822681 dihydrochloride

Catalog No.: A21470
dopamine D2 receptor antagonist
JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.
Grouped product items
Product Name Price Stock Qty
JNJ-37822681 dihydrochloride 5mg
$189.00
In stock
JNJ-37822681 dihydrochloride 10mg
$326.00
In stock
JNJ-37822681 dihydrochloride 50mg
$966.00
In stock
JNJ-37822681 dihydrochloride 100mg
$1,932.00
In stock
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Biological Activity
Discription JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.
Product Information
Catalog Num A21470
Formula C17H19Cl2F5N4
Molecular Weight 445.26
CAS Number 2108806-02-4
SMILES FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F.Cl.Cl
Synonyms JNJ37822681, JNJ 37822681
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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