JNJ-37822681 dihydrochloride

Catalog No.: A21470

dopamine D2 receptor antagonist

JNJ-37822681 dihydrochloride

JNJ-37822681 dihydrochloride Chemical Structure

CAS NO. 2108806-02-4

JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.

Availability: In stock

Package Price Qty
5 mg
$189.00
10 mg
$326.00
50 mg
$966.00
100 mg
$1,932.00
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Biological Activity

JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.46 mL 112.29 mL 224.59 mL
0.5 mM 4.49 mL 22.46 mL 44.92 mL
1 mM 2.25 mL 11.23 mL 22.46 mL
5 mM 0.45 mL 2.25 mL 4.49 mL

*The above data is based on the productmolecular weight 445.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21470
Actions Antagonist
M. Wt 445.26
Formula C17H19Cl2F5N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2108806-02-4
Synonyms JNJ37822681, JNJ 37822681
SMILES FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F.Cl.Cl

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