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JNJ-54119936

Name: JNJ-54119936
Brand: Adooq Bioscience
SKU: A77597
Availability: OutOfStock

Cat. No. A77597 CAS 1599531-55-1

RORγ Inverse Agonist

JNJ-54119936 is an inverse agonist of the retinoic acid receptor-related orphan receptor gamma (RORγ) with a Kd of 5.3 nM. This compound exhibits significant modulation of RORγ activity, making it valuable for research into autoimmune diseases and inflammatory responses. Its specific targeting of RORγ allows for the exploration of downstream signaling pathways and therapeutic applications in related biological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inverse Agonist
CAS Number	1599531-55-1
Applications	RORγ Inverse Agonist
Formula	C₃₄H₃₃ClN₄O₃
Molecular Weight	581.10
SMILES	O[C@@](C1CCN(CC1)C(C)=O)(C2=CC=CC=C2)C3=CC4=C(N=C(C(CC5=CC=C(N6C=CC=N6)C=C5)=C4Cl)OC)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.