JNJ-54175446

Name: JNJ-54175446
Brand: Adooq Bioscience
SKU: A18675
Rating: 5 (288 reviews)

Catalog No.: A18675

P2X7 receptor antagonist

JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.

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JNJ-54175446 1627902-21-9 P2X7 receptor antagonist

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Grouped product items
Size	Price	Stock
1mg	$285.00	In stock
5mg	$715.00	In stock
10mg	$980.00	In stock
25mg	$1,515.00	In stock
50mg	$1,975.00	In stock
100mg	$2,755.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.

Product Information

Catalog Num	A18675
Formula	C18H13ClF4N6O
Molecular Weight	440.78
CAS Number	1627902-21-9
SMILES	ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F
Synonyms	JNJ54175446, JNJ 54175446
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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