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JNK1 ligand-1-NH-Ph-COOH

JNK1 Inhibitor

JNK1 ligand-1-NH-Ph-COOH is a selective inhibitor of JNK1, targeting the c-Jun N-terminal kinase pathway. This compound enables the synthesis of various PROTAC molecules, including PROTAC JNK1-targeted-1, which is utilized in the investigation of pulmonary fibrosis. Its specific inhibition of JNK1 makes it a valuable tool for studying the mechanistic roles of this kinase in disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3047792-63-9
Applications	JNK1 Inhibitor
Formula	C₁₈H₁₄BrN₅O₃
Molecular Weight	428.24
SMILES	O=C(O)C1=CC=C(NC2=NC=C(Br)C(NC3=CC=CC=C3C(N)=O)=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.