JQAD1

Name: JQAD1
Brand: Adooq Bioscience
SKU: A23926
Rating: 5 (288 reviews)

Catalog No.: A23926

PROTAC EP300 Degrader

JQAD1 is a CRBN-dependent PROTAC selectively targeting EP300 for degradation. It effectively reduces EP300 protein levels and H3K27ac histone acetylation, resulting in apoptosis. JQAD1 is a valuable tool for investigating EP300 function and epigenetic regulation in cellular processes.

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JQAD1 2417097-18-6 PROTAC EP300 Degrader

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Grouped product items
Size	Price	Stock
5mg	$288.00	In stock
10mg	$496.00	In stock
50mg	$1,472.00	In stock
100mg	$2,880.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	JQAD1 is a CRBN-dependent PROTAC selectively targeting EP300 for degradation. It effectively reduces EP300 protein levels and H3K27ac histone acetylation, resulting in apoptosis. JQAD1 is a valuable tool for investigating EP300 function and epigenetic regulation in cellular processes.

Product Information

Catalog Num	A23926
Formula	C48H52F4N6O9
Molecular Weight	932.95
CAS Number	2417097-18-6
SMILES	O=C(N1CC(N([C@@H](C)C(F)(F)F)CC(C=C2)=CC=C2F)=O)[C@](CCC3=C4)(OC1=O)C3=CC=C4NC(CCCCCCCCCCCNC5=CC=C(C6=O)C(C(N6C(CCC7=O)C(N7)=O)=O)=C5)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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