JT001 sodium

Catalog No.: A35567
NLRP3 Inhibitor
JT001 sodium is a selective and orally bioavailable inhibitor of the NLRP3 inflammasome. By disrupting NLRP3 assembly, it effectively inhibits the release of pro-inflammatory cytokines and prevents pyroptosis. This compound is valuable for research into nonalcoholic steatohepatitis and liver fibrosis, providing insights into potential therapeutic strategies for these conditions.
Grouped product items
Size Price Stock Qty
5mg
$230.00
In stock
10mg
$380.00
In stock
25mg
$790.00
In stock
50mg
$1,230.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJT001 sodium is a selective and orally bioavailable inhibitor of the NLRP3 inflammasome. By disrupting NLRP3 assembly, it effectively inhibits the release of pro-inflammatory cytokines and prevents pyroptosis. This compound is valuable for research into nonalcoholic steatohepatitis and liver fibrosis, providing insights into potential therapeutic strategies for these conditions.
Product Information
Catalog NumA35567
FormulaC19H22N4NaO4S
Molecular Weight425.46
CAS Number2238820-09-0
SMILESO=C(NS(=O)(C1=C2OCCCN2N=C1)=O)NC3=C4CCCC4=CC5=C3CCC5.[Na]
SynonymsNLRP3-IN-19 sodium
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