Fig. 1 · Structure
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JTK-109
NS5B Inhibitor
JTK-109 is a potent inhibitor of the hepatitis C virus NS5B RNA-dependent RNA polymerase. It exhibits significant inhibitory activity with an IC50 value of 0.017 μM. This compound is primarily utilized in the research of hepatitis C virus (HCV), aiding in the study of viral replication mechanisms and potential therapeutic developments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 480462-62-2 |
| Applications | NS5B Inhibitor |
| Formula | C37H33ClFN3O4 |
| Molecular Weight | 638.13 |
| SMILES | O=C(C1=CC=C2C(N=C(C3=CC=C(OCC4=CC(N5C(CCC5)=O)=CC=C4C6=CC=C(Cl)C=C6)C=C3F)N2C7CCCCC7)=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.