Fig. 1 · Structure
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JTS-653
Cat. No.
A68798
CAS
942614-99-5
TRPV1 Antagonist
JTS-653 is a potent and selective antagonist of the transient receptor potential vanilloid 1 (TRPV1) channel. It demonstrates significant efficacy in attenuating chronic pain that is resistant to non-steroidal anti-inflammatory medications. This compound is valuable for research into pain management and the mechanisms underlying TRPV1-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 942614-99-5 |
| Applications | TRPV1 Antagonist |
| Formula | C23H21F3N4O4 |
| Molecular Weight | 474.43 |
| SMILES | OC[C@@H]1N(C(N=C2)=CC=C2C)C3=CC=CC(C(NC(C=C4)=CN=C4OCC(F)(F)F)=O)=C3OC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.