Fig. 1 · Structure
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JW 618
ABHD6 Inhibitor
JW 618 is a selective inhibitor of the enzyme ABHD6, exhibiting IC50 values of 38 nM and 13 nM for mouse and rat ABHD6, respectively. This compound plays a crucial role in lipid metabolism and can be utilized in research focused on the modulation of endocannabinoid signaling pathways. Its specific action on ABHD6 makes it a valuable tool for studying processes related to neuroprotection and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1416133-88-4 |
| Applications | ABHD6 Inhibitor |
| Formula | C17H14F6N2O2 |
| Molecular Weight | 392.30 |
| SMILES | O=C(N(CC1=CC(C2=CC=NC=C2)=CC=C1)C)OC(C(F)(F)F)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.