Fig. 1 · Structure
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JX237
SLC6A19 Inhibitor
JX237 is a potent inhibitor of the epithelial neutral amino acid transporter B0AT1 (SLC6A19), displaying an IC50 value of 31 nM. SLC6A19 plays a crucial role in the intestinal absorption and renal reabsorption of neutral amino acids. This inhibition can be utilized in research on disorders related to amino acid metabolism, providing insights into related pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1021125-90-5 |
| Applications | SLC6A19 Inhibitor |
| Formula | C11H15BrN2O |
| Molecular Weight | 271.15 |
| SMILES | BrC1=C(C)C=C(NCC(NCC)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.