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JYL-273 analog-1

Name: JYL-273 analog-1
Brand: Adooq Bioscience
SKU: A68840
Availability: OutOfStock

Cat. No. A68840 CAS 289902-71-2

TRPV1 Agonist

JYL-273 analog-1 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) ion channel, exhibiting a Ki value of 10.8 nM. This compound demonstrates significant analgesic activity, with an ED50 of 1.0 mg/kg in the PBQ-induced writhing test. JYL-273 analog-1 is suitable for investigations into pain mechanisms and the development of analgesic therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	289902-71-2
Applications	TRPV1 Agonist
Formula	C₂₈H₄₀N₂O₄S
Molecular Weight	500.69
SMILES	CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C(C)(C)C)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.