JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A20413
Formula
C16H26N4O3S
Molecular Weight
354.47
CAS Number
1672691-74-5
SMILES
O=C(OC1=NSN=C1N2CCOCC2)N(C3CCCCCCC3)C
Synonyms
JZP430, JZP 430
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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