Fig. 1 · Structure
Documents & Downloads
JZP-MA-11
ABHD6 Inhibitor
JZP-MA-11 is a selective inhibitor of the enzyme α/β-hydrolase domain 6 (ABHD6), with an IC50 value of 126 nM. This brain-penetrant compound serves as a positron emission tomography (PET) ligand, facilitating the investigation of ABHD6's role in the endocannabinoid system. JZP-MA-11 is suitable for preclinical studies in both mice and nonhuman primates, providing valuable insights into the biological functions and therapeutic potential of targeting ABHD6 in neurological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1672691-50-7 |
| Applications | ABHD6 Inhibitor |
| Formula | C15H17FN4O2S |
| Molecular Weight | 336.38 |
| SMILES | FC1=CC=C(C=C1)N(C)C(OC2=NSN=C2N3CCCCC3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.