Fig. 1 · Structure

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JZP-MA-13

ABHD6 Inhibitor

JZP-MA-13 is a selective inhibitor of α/β-hydrolase domain 6 (ABHD6), demonstrating an IC50 of 392 nM. This compound exhibits specificity by not inhibiting monoacylglycerol lipase (MAGL), ABHD12, fatty acid amide hydrolase (FAAH), or other serine hydrolases. JZP-MA-13 is also a positron emission tomography (PET) ligand, making it useful for in vivo imaging studies focused on ABHD6 activity and related physiological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3034900-00-7
Applications ABHD6 Inhibitor
Formula C14H15FN4O3S
Molecular Weight 338.36
SMILES
FC1=CC=C(C=C1)N(C)C(OC2=NSN=C2N3CCOCC3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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