K02288

Catalog No.: A14311

BMP inhibitor

K02288 Chemical Structure

CAS NO. 1431985-92-0

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $56.00

25 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $200.00

Special Price $160.00

10mM * 1mL in DMSO
$85.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.
Targets
Target Value
ALK2IC50: 1.1nM
ALK1IC50: 1.8nM
ALK6IC50: 6.4nM
ALK3IC50: 34.4nM
ALK4IC50: 302nM
ALK5IC50: 321nM
In vitro DMSO 70 mg/mL (198.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.38 mL 141.89 mL 283.78 mL
0.5 mM 5.68 mL 28.38 mL 56.76 mL
1 mM 2.84 mL 14.19 mL 28.38 mL
5 mM 0.57 mL 2.84 mL 5.68 mL

*The above data is based on the productmolecular weight 352.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14311
Actions Inhibitor
M. Wt 352.38
Formula C20H20N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1431985-92-0
Synonyms K 02288, K-02288
SMILES COC1=CC(=CC(=C1OC)OC)C2=C(N=CC(=C2)C3=CC(=CC=C3)O)N

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