K027

Catalog No.: A78687
AChE Inhibitor
K027 is a potent reactivator of acetylcholinesterase (AChE) inhibited by organophosphates (OP). It effectively restores AChE activity, making it valuable for studying neurodegenerative conditions such as Alzheimer's disease. K027's mechanism and specificity provide a useful tool for investigating therapeutic strategies targeting cholinergic dysfunction.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionK027 is a potent reactivator of acetylcholinesterase (AChE) inhibited by organophosphates (OP). It effectively restores AChE activity, making it valuable for studying neurodegenerative conditions such as Alzheimer's disease. K027's mechanism and specificity provide a useful tool for investigating therapeutic strategies targeting cholinergic dysfunction.
Product Information
Catalog NumA78687
FormulaC15H18Br2N4O2
Molecular Weight446.14
CAS Number6586-37-4
SMILESO=C(C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1)N.[Br-].[Br-]
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