Fig. 1 · Structure
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KAR425
Antimalarial Agent
KAR425 is a potent antimalarial agent that exhibits efficacy against multiple strains of Plasmodium falciparum. It demonstrates activity against both Chloroquine-sensitive (CQS) D6 and Chloroquine-resistant (CQR) Dd2 and 7G8 strains, with IC50 values of 62 nM, 55 nM, and 60 nM, respectively. This compound is valuable for research focused on malaria treatment and resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1809050-49-4 |
| Applications | Antimalarial Agent |
| Formula | C19H27N3 |
| Molecular Weight | 297.44 |
| SMILES | CCC1=C(C)/C(N=C1C2=CC=CN2)=C\NC3CCCCCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.