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Karenitecin-NH2

Camptothecin Analogue

Karenitecin-NH2 is a Camptothecin analogue that functions through the inhibition of topoisomerase I, leading to the prevention of DNA replication in cancer cells. It exhibits significant antitumor activity, making it a valuable compound for cancer research and the development of novel therapeutic agents. This reagent is useful for studying the mechanisms of drug resistance and for evaluating new strategies in cancer treatment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	276250-52-3
Applications	Camptothecin Analogue
Formula	C₂₅H₂₉N₃O₄Si
Molecular Weight	463.60
Synonyms	Cositecan-NH2; BNP 1350-NH2
SMILES	C[Si](C)(C)CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(N)C=C51

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.