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KAT6A/KAT7-IN-3

KAT6A/KAT7 Inhibitor

KAT6A/KAT7-IN-3 is a potent inhibitor of KAT6A and KAT7, exhibiting an IC50 of ≤ 50 nM for KAT6A and ≤ 1 nM for KAT7. This compound effectively inhibits the acetylation of histones H3K14 and H3K23, which is crucial for regulating gene expression. KAT6A/KAT7-IN-3 demonstrates significant anti-proliferative activity against tumor cells, with an IC50 of > 2 μM and ≤ 5 μM in CAMA-1 cell lines. This reagent is valuable for studies exploring cancer biology and the roles of histone acetylation in tumorigenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3092066-83-3
Applications	KAT6A/KAT7 Inhibitor
Formula	C₂₄H₂₄N₄O₆S
Molecular Weight	496.54
SMILES	O=S(C1=C(OC)C=CN=C1OC)(NC2=NOC3=C2CC4(C5=C3C=C(N6C(CCC6)=O)C=C5)CC4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.