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HDAC inhibitor
In Stock
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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| HeLa | EC50 | 25 nM | Inhibition of HDAC in human HeLa cells assessed as histone H3 hyperacetylation after 7 hrs | 10.1039/C1MD00199J |
| HeLa | EC50 | 325 nM | Inhibition of HDAC in human HeLa cells assessed as alpha-tubulin acetylation after 7 hrs | 10.1039/C1MD00199J |
| HeLa | IC50 | 45 nM | Inhibition of HDAC isolated from human HeLa cell nuclear extracts using Fluor de Lys as substrate after 30 mins by fluorescence assay | 10.1039/C1MD00199J |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 940943-37-3 |
| Applications | HDAC inhibitor |
| Formula | C20H25N3O5S2 |
| Molecular Weight | 451.56 |
| SMILES | CC(=O)SCC(=O)C1=CN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)OCCCN(C)C |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
