KEA1-97 is a selective disruptor of the thioredoxin-caspase 3 interaction, exhibiting an IC50 of 10 μM. This compound effectively disrupts the binding of thioredoxin to caspase 3, leading to the activation of caspases and subsequent induction of apoptosis, while preserving thioredoxin's enzymatic function. KEA1-97 is valuable for research into apoptosis mechanisms and therapeutic strategies targeting cell death pathways.
KEA1-97 is a selective disruptor of the thioredoxin-caspase 3 interaction, exhibiting an IC50 of 10 μM. This compound effectively disrupts the binding of thioredoxin to caspase 3, leading to the activation of caspases and subsequent induction of apoptosis, while preserving thioredoxin's enzymatic function. KEA1-97 is valuable for research into apoptosis mechanisms and therapeutic strategies targeting cell death pathways.
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