Kevetrin (3-Cyanopropyl carbamimidothioate; 4-Isothioureidobutyronitrile) is an apoptosis inducer that functions through both p53-dependent and p53-independent mechanisms. It activates and stabilizes the p53 protein in TP53 wild-type models by modulating MDM2 processing, leading to cell cycle arrest and apoptosis. Additionally, Kevetrin demonstrates enhanced efficacy in models with mutated TP53. This compound is valuable for research applications in various cancers, including acute myeloid leukemia and breast cancer.
Kevetrin (3-Cyanopropyl carbamimidothioate; 4-Isothioureidobutyronitrile) is an apoptosis inducer that functions through both p53-dependent and p53-independent mechanisms. It activates and stabilizes the p53 protein in TP53 wild-type models by modulating MDM2 processing, leading to cell cycle arrest and apoptosis. Additionally, Kevetrin demonstrates enhanced efficacy in models with mutated TP53. This compound is valuable for research applications in various cancers, including acute myeloid leukemia and breast cancer.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
