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KF15766

TXA2/H1 antagonist

KF15766 is an orally active dual antagonist of thromboxane A2 (TXA2) and histamine H1 receptors, exhibiting inhibition constants (Kis) of 740 nM and 20 nM, respectively. This compound demonstrates significant potential for therapeutic applications in antiallergic research, allowing for the exploration of its effects on allergic responses and related disorders. Its dual-target mechanism makes KF15766 an important tool in the study of asthma and other allergic conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	124907-44-4
Applications	TXA2/H1 antagonist
Formula	C₃₀H₃₁NO₃.1/2C₄H₄O₄
Molecular Weight	511.62
SMILES	O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C/CN4CCC(CC5=CC=CC=C5)CC4.O=C(O)/C=C/C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.