KF15766

Catalog No.: A63191
TXA2/H1 antagonist
KF15766 is an orally active dual antagonist of thromboxane A2 (TXA2) and histamine H1 receptors, exhibiting inhibition constants (Kis) of 740 nM and 20 nM, respectively. This compound demonstrates significant potential for therapeutic applications in antiallergic research, allowing for the exploration of its effects on allergic responses and related disorders. Its dual-target mechanism makes KF15766 an important tool in the study of asthma and other allergic conditions.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionKF15766 is an orally active dual antagonist of thromboxane A2 (TXA2) and histamine H1 receptors, exhibiting inhibition constants (Kis) of 740 nM and 20 nM, respectively. This compound demonstrates significant potential for therapeutic applications in antiallergic research, allowing for the exploration of its effects on allergic responses and related disorders. Its dual-target mechanism makes KF15766 an important tool in the study of asthma and other allergic conditions.
Product Information
Catalog NumA63191
FormulaC30H31NO3.1/2C4H4O4
Molecular Weight511.62
CAS Number124907-44-4
SMILESO=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C/CN4CCC(CC5=CC=CC=C5)CC4.O=C(O)/C=C/C(O)=O.[1/2]
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