Fig. 1 · Structure
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KF38789
P-selectin Inhibitor
KF38789 is a selective inhibitor of P-selectin, specifically targeting the P-selectin-PSGL-1 interaction. It effectively inhibits the adhesion of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein, exhibiting an IC50 value of 1.97 μM. This compound is valuable for studies focused on cell adhesion mechanisms, inflammatory response research, and potential therapeutic interventions in diseases involving P-selectin.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 257292-29-8 |
| Applications | P-selectin Inhibitor |
| Formula | C19H21NO5S |
| Molecular Weight | 375.44 |
| SMILES | O=C1OC(C)=CC(O)=C1C2=NCCSC(C2)C3=CC=C(C=C3OC)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.