Fig. 1 · Structure
Documents & Downloads
KM-001-E2
Cat. No.
B10862
CAS
2682864-43-1
KM-001 Isomer
KM-001-E2 is the (S)-enantiomer of KM-001, a selective antagonist of the TRPV3 channel. This compound plays a significant role in investigating the mechanisms underlying skin itching and keratinization disorders. Its application in research may provide insights into TRPV3-related pathophysiology and potential therapeutic strategies for skin conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2682864-43-1 |
| Applications | KM-001 Isomer |
| Formula | C26H25FN2O2 |
| Molecular Weight | 416.49 |
| Synonyms | (S)-KM-001 |
| SMILES | OCC1=C([C@H]2CN(CC2)C(C3=CC=C(C=N3)F)=O)C=CC(C4=C(C5CC5)C=CC=C4)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.